Which cardiac biomarker is the most sensitive and specific for myocardial injury?

Answer

Troponin (specifically Troponin I and Troponin T) is the preferred cardiac biomarker because it is both the most sensitive and most specific indicator of myocardial necrosis (heart muscle injury). CK-MB is less specific, myoglobin is sensitive but lacks specificity, and BNP is used primarily for assessing heart failure rather than acute myocardial infarction.